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Sequence Complexity of Amyloidogenic Regions in Intrinsically Disordered Human Proteins

An amyloidogenic region (AR) in a protein sequence plays a significant role in protein aggregation and amyloid formation. We have investigated the sequence complexity of AR that is present in intrinsically disordered human proteins. More than 80% human proteins in the disordered protein databases (D...

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Detalles Bibliográficos
Autores principales: Das, Swagata, Pal, Uttam, Das, Supriya, Bagga, Khyati, Roy, Anupam, Mrigwani, Arpita, Maiti, Nakul C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940659/
https://www.ncbi.nlm.nih.gov/pubmed/24594841
http://dx.doi.org/10.1371/journal.pone.0089781