Lipopolysaccharide Induces Inflammatory Hyperalgesia Triggering a TLR4/MyD88-Dependent Cytokine Cascade in the Mice Paw

Inflammatory pain can be triggered by different stimuli, such as trauma, radiation, antigen and infection. In a model of inflammatory pain caused by infection, injection in the mice paw of lipopolysaccharide (LPS), a Toll-like receptor 4 (TLR4) agonist, produces mechanical hyperalgesia. We identify...

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Detalles Bibliográficos
Autores principales: Calil, Igor L., Zarpelon, Ana C., Guerrero, Ana T. G., Alves-Filho, Jose C., Ferreira, Sergio H., Cunha, Fernando Q., Cunha, Thiago M., Verri, Waldiceu A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940714/
https://www.ncbi.nlm.nih.gov/pubmed/24595131
http://dx.doi.org/10.1371/journal.pone.0090013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940714/
https://www.ncbi.nlm.nih.gov/pubmed/24595131
http://dx.doi.org/10.1371/journal.pone.0090013

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