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Lipopolysaccharide Induces Inflammatory Hyperalgesia Triggering a TLR4/MyD88-Dependent Cytokine Cascade in the Mice Paw

Inflammatory pain can be triggered by different stimuli, such as trauma, radiation, antigen and infection. In a model of inflammatory pain caused by infection, injection in the mice paw of lipopolysaccharide (LPS), a Toll-like receptor 4 (TLR4) agonist, produces mechanical hyperalgesia. We identify...

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Detalles Bibliográficos
Autores principales:	Calil, Igor L., Zarpelon, Ana C., Guerrero, Ana T. G., Alves-Filho, Jose C., Ferreira, Sergio H., Cunha, Fernando Q., Cunha, Thiago M., Verri, Waldiceu A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940714/ https://www.ncbi.nlm.nih.gov/pubmed/24595131 http://dx.doi.org/10.1371/journal.pone.0090013

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