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Physiological Role of Kv1.3 Channel in T Lymphocyte Cell Investigated Quantitatively by Kinetic Modeling

Kv1.3 channel is a delayed rectifier channel abundant in human T lymphocytes. Chronic inflammatory and autoimmune disorders lead to the over-expression of Kv1.3 in T cells. To quantitatively study the regulatory mechanism and physiological function of Kv1.3 in T cells, it is necessary to have a prec...

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Detalles Bibliográficos
Autores principales: Hou, Panpan, Zhang, Rong, Liu, Yongfeng, Feng, Jing, Wang, Wei, Wu, Yingliang, Ding, Jiuping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940720/
https://www.ncbi.nlm.nih.gov/pubmed/24594979
http://dx.doi.org/10.1371/journal.pone.0089975