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The Chaperone BAG6 Captures Dislocated Glycoproteins in the Cytosol
Secretory and membrane (glyco)proteins are subject to quality control in the endoplasmic reticulum (ER) to ensure that only functional proteins reach their destination. Proteins deemed terminally misfolded and hence functionally defective may be dislocated to the cytosol, where the proteasome degrad...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940849/ https://www.ncbi.nlm.nih.gov/pubmed/24594942 http://dx.doi.org/10.1371/journal.pone.0090204 |