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Maternal Nutrition Induces Pervasive Gene Expression Changes but No Detectable DNA Methylation Differences in the Liver of Adult Offspring

AIMS: Epidemiological and animal studies have shown that maternal diet can influence metabolism in adult offspring. However, the molecular mechanisms underlying these changes remain poorly understood. Here, we characterize the phenotypes induced by maternal obesity in a mouse model and examine gene...

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Detalles Bibliográficos
Autores principales: Cannon, Matthew V., Buchner, David A., Hester, James, Miller, Hadley, Sehayek, Ephraim, Nadeau, Joseph H., Serre, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940881/
https://www.ncbi.nlm.nih.gov/pubmed/24594983
http://dx.doi.org/10.1371/journal.pone.0090335