Ex Vivo Expanded Human Regulatory T Cells Delay Islet Allograft Rejection via Inhibiting Islet-Derived Monocyte Chemoattractant Protein-1 Production in CD34(+) Stem Cells-Reconstituted NOD-scid IL2rγ(null) Mice

Type 1 diabetes mellitus (T1DM) is an autoimmune disease caused by immune-mediated destruction of insulin-secreting β cells of the pancreas. Near complete dependence on exogenous insulin makes T1DM very difficult to control, with the result that patients are exposed to high blood glucose and risk of...

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Detalles Bibliográficos
Autores principales: Xiao, Fang, Ma, Liang, Zhao, Min, Huang, Guocai, Mirenda, Vincenzo, Dorling, Anthony, Lechler, Robert, Lombardi, Giovanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940883/
https://www.ncbi.nlm.nih.gov/pubmed/24594640
http://dx.doi.org/10.1371/journal.pone.0090387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940883/
https://www.ncbi.nlm.nih.gov/pubmed/24594640
http://dx.doi.org/10.1371/journal.pone.0090387

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