New Insights into Transcription Fidelity: Thermal Stability of Non-Canonical Structures in Template DNA Regulates Transcriptional Arrest, Pause, and Slippage

The thermal stability and topology of non-canonical structures of G-quadruplexes and hairpins in template DNA were investigated, and the effect of non-canonical structures on transcription fidelity was evaluated quantitatively. We designed ten template DNAs: A linear sequence that does not have sign...

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Detalles Bibliográficos
Autores principales: Tateishi-Karimata, Hisae, Isono, Noburu, Sugimoto, Naoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940900/
https://www.ncbi.nlm.nih.gov/pubmed/24594642
http://dx.doi.org/10.1371/journal.pone.0090580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940900/
https://www.ncbi.nlm.nih.gov/pubmed/24594642
http://dx.doi.org/10.1371/journal.pone.0090580

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