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GRK5 Intronic (CA)(n) Polymorphisms Associated with Type 2 Diabetes in Chinese Hainan Island

A genome-wide association study had showed G-protein–coupled receptor kinase 5 (GRK5) rs10886471 was related to the risk of type 2 diabetes mellitus (T2DM) through upregulated GRK5 mRNA expression. Rs10886471 is located in the intron region of GRK5. However, the mechanism by which intronic SNP affec...

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Detalles Bibliográficos
Autores principales: Xia, Zhenfang, Yang, Tubao, Wang, Zhuansuo, Dong, Jianping, Liang, Chunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940906/
https://www.ncbi.nlm.nih.gov/pubmed/24594703
http://dx.doi.org/10.1371/journal.pone.0090597