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Serum levels of mature microRNAs in DICER1-mutated pleuropulmonary blastoma

DICER1 is a critical gene in the biogenesis of mature microRNAs, short non-coding RNAs that derive from either -3p or -5p precursor microRNA strands. Germline mutations of DICER1 are associated with a range of human malignancies, including pleuropulmonary blastoma (PPB). Additional somatic ‘hotspot&...

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Detalles Bibliográficos
Autores principales: Murray, M J, Bailey, S, Raby, K L, Saini, H K, de Kock, L, Burke, G A A, Foulkes, W D, Enright, A J, Coleman, N, Tischkowitz, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940920/
https://www.ncbi.nlm.nih.gov/pubmed/24513630
http://dx.doi.org/10.1038/oncsis.2014.1