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Discrimination of the Expression of Paralogous microRNA Precursors That Share the Same Major Mature Form

BACKGROUND: MicroRNAs (miRNAs) are a class of small non-coding RNAs generated from endogenous transcripts that form hairpin structures. The hairpin precursor is processed into two mature miRNAs that form major/minor duplexes. Mature miRNAs regulate gene expression by cleaving mRNA or repressing prot...

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Detalles Bibliográficos
Autores principales: Wang, Minghua, Wang, Weiping, Zhang, Ping, Xiao, Juanjuan, Wang, Jianguo, Huang, Chaoqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940925/
https://www.ncbi.nlm.nih.gov/pubmed/24594692
http://dx.doi.org/10.1371/journal.pone.0090591