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Macrophage Contact Dependent and Independent TLR4 Mechanisms Induce β-Cell Dysfunction and Apoptosis in a Mouse Model of Type 2 Diabetes
Type 2 diabetes (T2D) is evolving into a global disease and patients have a systemic low-grade inflammation, yet the role of this inflammation is still not established. One plausible mechanism is enhanced expression and activity of the innate immune system. Therefore, we evaluated the expression and...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940939/ https://www.ncbi.nlm.nih.gov/pubmed/24594974 http://dx.doi.org/10.1371/journal.pone.0090685 |