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Osteosarcoma Microenvironment: Whole-Slide Imaging and Optimized Antigen Detection Overcome Major Limitations in Immunohistochemical Quantification

BACKGROUND: In osteosarcoma survival rates could not be improved over the last 30 years. Novel biomarkers are warranted to allow risk stratification of patients for more individual treatment following initial diagnosis. Although previous studies of the tumor microenvironment have identified promisin...

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Detalles Bibliográficos
Autores principales: Kunz, Pierre, Fellenberg, Jörg, Moskovszky, Linda, Sápi, Zoltan, Krenacs, Tibor, Poeschl, Johannes, Lehner, Burkhard, Szendrõi, Miklos, Ewerbeck, Volker, Kinscherf, Ralf, Fritzsching, Benedikt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940945/
https://www.ncbi.nlm.nih.gov/pubmed/24594971
http://dx.doi.org/10.1371/journal.pone.0090727