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Osteosarcoma Microenvironment: Whole-Slide Imaging and Optimized Antigen Detection Overcome Major Limitations in Immunohistochemical Quantification
BACKGROUND: In osteosarcoma survival rates could not be improved over the last 30 years. Novel biomarkers are warranted to allow risk stratification of patients for more individual treatment following initial diagnosis. Although previous studies of the tumor microenvironment have identified promisin...
Autores principales: | Kunz, Pierre, Fellenberg, Jörg, Moskovszky, Linda, Sápi, Zoltan, Krenacs, Tibor, Poeschl, Johannes, Lehner, Burkhard, Szendrõi, Miklos, Ewerbeck, Volker, Kinscherf, Ralf, Fritzsching, Benedikt |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940945/ https://www.ncbi.nlm.nih.gov/pubmed/24594971 http://dx.doi.org/10.1371/journal.pone.0090727 |
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