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Study of Protein Haptenation by Amoxicillin Through the Use of a Biotinylated Antibiotic
Allergic reactions towards β-lactam antibiotics pose an important clinical problem. The ability of small molecules, such as a β-lactams, to bind covalently to proteins, in a process known as haptenation, is considered necessary for induction of a specific immunological response. Identification of th...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940954/ https://www.ncbi.nlm.nih.gov/pubmed/24595455 http://dx.doi.org/10.1371/journal.pone.0090891 |