Structural analysis of human 2′-O-ribose methyltransferases involved in mRNA cap structure formation

The 5′ cap of human messenger RNA contains 2′-O-methylation of the first and often second transcribed nucleotide that is important for its processing, translation and stability. Human enzymes that methylate these nucleotides, termed CMTr1 and CMTr2, respectively, have recently been identified. Howev...

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Detalles Bibliográficos
Autores principales: Smietanski, Miroslaw, Werner, Maria, Purta, Elzbieta, Kaminska, Katarzyna H., Stepinski, Janusz, Darzynkiewicz, Edward, Nowotny, Marcin, Bujnicki, Janusz M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941023/
https://www.ncbi.nlm.nih.gov/pubmed/24402442
http://dx.doi.org/10.1038/ncomms4004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941023/
https://www.ncbi.nlm.nih.gov/pubmed/24402442
http://dx.doi.org/10.1038/ncomms4004

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