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Pharmacogenomics of selective serotonin reuptake inhibitor treatment for major depressive disorder: genome-wide associations and functional genomics

A genome-wide association (GWA) study of treatment outcomes (response and remission) of selective serotonin reuptake inhibitors (SSRIs) was conducted using 529 subjects with major depressive disorder (MDD). While no SNP associations reached the genome-wide level of significance, 14 SNPs of interest...

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Detalles Bibliográficos
Autores principales: Ji, Yuan, Biernacka, Joanna M., Hebbring, Scott, Chai, Yubo, Jenkins, Gregory D., Batzler, Anthony, Snyder, Karen A., Drews, Maureen S., Desta, Zeruesenay, Flockhart, David, Mushiroda, Taisei, Kubo, Michiaki, Nakamura, Yusuke, Kamatani, Naoyuki, Schaid, Daniel, Weinshilboum, Richard M., Mrazek, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941038/
https://www.ncbi.nlm.nih.gov/pubmed/22907730
http://dx.doi.org/10.1038/tpj.2012.32