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Caveolae regulate the nanoscale organization of the plasma membrane to remotely control Ras signaling

The molecular mechanisms whereby caveolae exert control over cellular signaling have to date remained elusive. We have therefore explored the role caveolae play in modulating Ras signaling. Lipidomic and gene array analyses revealed that caveolin-1 (CAV1) deficiency results in altered cellular lipid...

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Detalles Bibliográficos
Autores principales: Ariotti, Nicholas, Fernández-Rojo, Manuel A., Zhou, Yong, Hill, Michelle M., Rodkey, Travis L., Inder, Kerry L., Tanner, Lukas B., Wenk, Markus R., Hancock, John F., Parton, Robert G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941050/
https://www.ncbi.nlm.nih.gov/pubmed/24567358
http://dx.doi.org/10.1083/jcb.201307055