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Caveolae regulate the nanoscale organization of the plasma membrane to remotely control Ras signaling
The molecular mechanisms whereby caveolae exert control over cellular signaling have to date remained elusive. We have therefore explored the role caveolae play in modulating Ras signaling. Lipidomic and gene array analyses revealed that caveolin-1 (CAV1) deficiency results in altered cellular lipid...
Autores principales: | Ariotti, Nicholas, Fernández-Rojo, Manuel A., Zhou, Yong, Hill, Michelle M., Rodkey, Travis L., Inder, Kerry L., Tanner, Lukas B., Wenk, Markus R., Hancock, John F., Parton, Robert G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941050/ https://www.ncbi.nlm.nih.gov/pubmed/24567358 http://dx.doi.org/10.1083/jcb.201307055 |
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