Live Multicellular Tumor Spheroid Models For High-Content Imaging and Screening In Cancer Drug Discovery

The multi cellular tumor spheroid (MCTS) model has been used for decades with proven superiority over monolayer cell culture models at recapitulating in vivo tumor growth. Yet its use in high-throughput drug discovery has been limited, particularly with image based screening, due to practical and te...

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Detalles Bibliográficos
Autores principales: Reid, Brian G., Jerjian, Taleen, Patel, Purvi, Zhou, Qiong, Yoo, Byong Hoon, Kabos, Peter, Sartorius, Carol A., LaBarbera, Daniel V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941083/
https://www.ncbi.nlm.nih.gov/pubmed/24596682
http://dx.doi.org/10.2174/2213988501408010027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941083/
https://www.ncbi.nlm.nih.gov/pubmed/24596682
http://dx.doi.org/10.2174/2213988501408010027

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