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Identifying Small Molecules which Inhibit Autophagy: a Phenotypic Screen Using Image-Based High-Content Cell Analysis

Autophagy plays an important role in cancer and it has been suggested that it functions not only as a tumor suppressor pathway to prevent tumor initiation, but also as a pro-survival pathway that helps tumor cells endure metabolic stress and resist death triggered by chemotherapeutic agents, includi...

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Detalles Bibliográficos
Autores principales: Peppard, J.V., Rugg, C., Smicker, M., Dureuil, C., Ronan, B., Flamand, O., Durand, L., Pasquier, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941084/
https://www.ncbi.nlm.nih.gov/pubmed/24596680
http://dx.doi.org/10.2174/2213988501408010003