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Identifying Small Molecules which Inhibit Autophagy: a Phenotypic Screen Using Image-Based High-Content Cell Analysis
Autophagy plays an important role in cancer and it has been suggested that it functions not only as a tumor suppressor pathway to prevent tumor initiation, but also as a pro-survival pathway that helps tumor cells endure metabolic stress and resist death triggered by chemotherapeutic agents, includi...
Autores principales: | Peppard, J.V., Rugg, C., Smicker, M., Dureuil, C., Ronan, B., Flamand, O., Durand, L., Pasquier, B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Open
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941084/ https://www.ncbi.nlm.nih.gov/pubmed/24596680 http://dx.doi.org/10.2174/2213988501408010003 |
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