Principles of nucleation of H3K27 methylation during embryonic development

During embryonic development, maintenance of cell identity and lineage commitment requires the Polycomb-group PRC2 complex, which catalyzes histone H3 lysine 27 trimethylation (H3K27me3). However, the developmental origins of this regulation are unknown. Here we show that H3K27me3 enrichment increas...

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Detalles Bibliográficos
Autores principales: van Heeringen, Simon J., Akkers, Robert C., van Kruijsbergen, Ila, Arif, M. Asif, Hanssen, Lars L.P., Sharifi, Nilofar, Veenstra, Gert Jan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941105/
https://www.ncbi.nlm.nih.gov/pubmed/24336765
http://dx.doi.org/10.1101/gr.159608.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941105/
https://www.ncbi.nlm.nih.gov/pubmed/24336765
http://dx.doi.org/10.1101/gr.159608.113

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