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Principles of nucleation of H3K27 methylation during embryonic development
During embryonic development, maintenance of cell identity and lineage commitment requires the Polycomb-group PRC2 complex, which catalyzes histone H3 lysine 27 trimethylation (H3K27me3). However, the developmental origins of this regulation are unknown. Here we show that H3K27me3 enrichment increas...
Autores principales: | van Heeringen, Simon J., Akkers, Robert C., van Kruijsbergen, Ila, Arif, M. Asif, Hanssen, Lars L.P., Sharifi, Nilofar, Veenstra, Gert Jan C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941105/ https://www.ncbi.nlm.nih.gov/pubmed/24336765 http://dx.doi.org/10.1101/gr.159608.113 |
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