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From single-cell to cell-pool transcriptomes: Stochasticity in gene expression and RNA splicing
Single-cell RNA-seq mammalian transcriptome studies are at an early stage in uncovering cell-to-cell variation in gene expression, transcript processing and editing, and regulatory module activity. Despite great progress recently, substantial challenges remain, including discriminating biological va...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941114/ https://www.ncbi.nlm.nih.gov/pubmed/24299736 http://dx.doi.org/10.1101/gr.161034.113 |