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Chemo-enzymatic Synthesis of Propionyl-ester-linked Taxol-monosaccharide Conjugate and its Drug Delivery System Using Hybrid-Bio-nanocapsules Targeting Brain Glioma Cells

Taxol is recognized as one of the most potent anticancer agents used in the treatment of breast and ovarian cancers, which are common cancers in women. To overcome its shortcomings, that is, its low water-solubility that reduces drug loading capacity of DDS carriers when incorporating taxol, chemo-e...

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Detalles Bibliográficos
Autores principales: Hamada, Hiroki, Shimoda, Kei, Seno, Masaharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941184/
https://www.ncbi.nlm.nih.gov/pubmed/24665217
http://dx.doi.org/10.4137/CMWH.S8213