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Decompensation of β-Cells in Diabetes: When Pancreatic β-Cells Are on ICE(R)
Insulin production and secretion are temporally regulated. Keeping insulin secretion at rest after a rise of glucose prevents exhaustion and ultimately failure of β-cells. Among the mechanisms that reduce β-cell activity is the inducible cAMP early repressor (ICER). ICER is an immediate early gene,...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi Publishing Corporation
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941242/ https://www.ncbi.nlm.nih.gov/pubmed/24672804 http://dx.doi.org/10.1155/2014/768024 |