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Role of ATF-2 in regulation of epithelial–mesenchymal transition and radio-sensitivity of A549 cells mediated by secreted soluble factors

INTRODUCTION: Epithelial–mesenchymal transition (EMT) is known to be a crucial event whereby cancer cells acquire the traits needed to execute multiple steps of metastasis [ 1]. Intriguingly, epithelial cancer cells undergoing EMT also exhibit increased radioresistance [ 2]. EMT is a dynamic process...

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Detalles Bibliográficos
Autores principales: Desai, Sejal, Laskar, S., Pandey, B. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941510/
http://dx.doi.org/10.1093/jrr/rrt162