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NF-kappaB-dependent MicroRNA-425 upregulation promotes gastric cancer cell growth by targeting PTEN upon IL-1β induction

Overexpression of the proinflammatory cytokine IL-1β is associated with diverse diseases, including cancer. Alteration of microRNAs has been observed in cancer cells exposed to proinflammatory cytokines, yet their function in inflammation stress remains elusive. Here, we show that IL-1β induces the...

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Detalles Bibliográficos
Autores principales: Ma, Jun, Liu, Jun, Wang, Zhiming, Gu, Xixi, Fan, Yue, Zhang, Wen, Xu, Lili, Zhang, Jianjun, Cai, Dingfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941686/
https://www.ncbi.nlm.nih.gov/pubmed/24571667
http://dx.doi.org/10.1186/1476-4598-13-40