An eEF1A1 truncation encoded by PTI-1 exerts its oncogenic effect inside the nucleus

BACKGROUND: The oncogene PTI-1 was originally isolated from a prostate cancer cell line by its capability to transform rat fibroblasts. The PTI-1 mRNA has a very eccentric structure as the 5′UTR is similar to prokaryotic 23S rRNA, while the major open reading frame and the 3′UTR corresponds to a par...

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Detalles Bibliográficos
Autores principales: Dahl, Louise D, Corydon, Thomas J, Ränkel, Liina, Nielsen, Karen Margrethe, Füchtbauer, Ernst-Martin, Knudsen, Charlotte R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941776/
https://www.ncbi.nlm.nih.gov/pubmed/24571548
http://dx.doi.org/10.1186/1475-2867-14-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941776/
https://www.ncbi.nlm.nih.gov/pubmed/24571548
http://dx.doi.org/10.1186/1475-2867-14-17

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