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Can we accurately report PTEN status in advanced colorectal cancer?

BACKGROUND: Loss of phosphatase and tensin homologue (PTEN) function evaluated by loss of PTEN protein expression on immunohistochemistry (IHC) has been reported as both prognostic in metastatic colorectal cancer and predictive of response to anti-EGFR monoclonal antibodies although results remain u...

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Detalles Bibliográficos
Autores principales: Hocking, Christopher, Hardingham, Jennifer E, Broadbridge, Vy, Wrin, Joe, Townsend, Amanda R, Tebbutt, Niall, Cooper, John, Ruszkiewicz, Andrew, Lee, Chee, Price, Timothy J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941793/
https://www.ncbi.nlm.nih.gov/pubmed/24564252
http://dx.doi.org/10.1186/1471-2407-14-128