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Can we accurately report PTEN status in advanced colorectal cancer?
BACKGROUND: Loss of phosphatase and tensin homologue (PTEN) function evaluated by loss of PTEN protein expression on immunohistochemistry (IHC) has been reported as both prognostic in metastatic colorectal cancer and predictive of response to anti-EGFR monoclonal antibodies although results remain u...
Autores principales: | Hocking, Christopher, Hardingham, Jennifer E, Broadbridge, Vy, Wrin, Joe, Townsend, Amanda R, Tebbutt, Niall, Cooper, John, Ruszkiewicz, Andrew, Lee, Chee, Price, Timothy J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941793/ https://www.ncbi.nlm.nih.gov/pubmed/24564252 http://dx.doi.org/10.1186/1471-2407-14-128 |
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