FISH Amyloid – a new method for finding amyloidogenic segments in proteins based on site specific co-occurence of aminoacids

BACKGROUND: Amyloids are proteins capable of forming fibrils whose intramolecular contact sites assume densely packed zipper pattern. Their oligomers can underlie serious diseases, e.g. Alzheimer’s and Parkinson’s diseases. Recent studies show that short segments of aminoacids can be responsible for...

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Detalles Bibliográficos
Autores principales: Gasior, Pawel, Kotulska, Malgorzata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941796/
https://www.ncbi.nlm.nih.gov/pubmed/24564523
http://dx.doi.org/10.1186/1471-2105-15-54

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941796/
https://www.ncbi.nlm.nih.gov/pubmed/24564523
http://dx.doi.org/10.1186/1471-2105-15-54

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