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Chronic stress enhances microglia activation and exacerbates death of nigral dopaminergic neurons under conditions of inflammation

BACKGROUND: Parkinson’s disease is an irreversible neurodegenerative disease linked to progressive movement disorders and is accompanied by an inflammatory reaction that is believed to contribute to its pathogenesis. Since sensitivity to inflammation is not the same in all brain structures, the aim...

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Detalles Bibliográficos
Autores principales: de Pablos, Rocío M, Herrera, Antonio J, Espinosa-Oliva, Ana M, Sarmiento, Manuel, Muñoz, Mario F, Machado, Alberto, Venero, José L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941799/
https://www.ncbi.nlm.nih.gov/pubmed/24565378
http://dx.doi.org/10.1186/1742-2094-11-34