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Unique Characteristics of the Pyrrolysine System in the 7th Order of Methanogens: Implications for the Evolution of a Genetic Code Expansion Cassette
Pyrrolysine (Pyl), the 22nd proteogenic amino acid, was restricted until recently to few organisms. Its translational use necessitates the presence of enzymes for synthesizing it from lysine, a dedicated amber stop codon suppressor tRNA, and a specific amino-acyl tRNA synthetase. The three genomes o...
Autores principales: | Borrel, Guillaume, Gaci, Nadia, Peyret, Pierre, O'Toole, Paul W., Gribaldo, Simonetta, Brugère, Jean-François |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941956/ https://www.ncbi.nlm.nih.gov/pubmed/24669202 http://dx.doi.org/10.1155/2014/374146 |
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