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IB4(+) and TRPV1(+) sensory neurons mediate pain but not proliferation in a mouse model of squamous cell carcinoma

BACKGROUND: Cancer pain severely limits function and significantly reduces quality of life. Subtypes of sensory neurons involved in cancer pain and proliferation are not clear. METHODS: We produced a cancer model by inoculating human oral squamous cell carcinoma (SCC) cells into the hind paw of athy...

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Detalles Bibliográficos
Autores principales: Ye, Yi, Bae, Sam S, Viet, Chi T, Troob, Scott, Bernabé, Daniel, Schmidt, Brian L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942073/
https://www.ncbi.nlm.nih.gov/pubmed/24524628
http://dx.doi.org/10.1186/1744-9081-10-5