N-Acetylcysteine prevents congenital heart defects induced by pregestational diabetes

BACKGROUND: Pregestational diabetes is a major risk factor of congenital heart defects (CHDs). Glutathione is depleted and reactive oxygen species (ROS) production is elevated in diabetes. In the present study, we aimed to examine whether treatment with N-acetylcysteine (NAC), which increases glutat...

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Detalles Bibliográficos
Autores principales: Moazzen, Hoda, Lu, Xiangru, Ma, Noelle L, Velenosi, Thomas J, Urquhart, Brad L, Wisse, Lambertus J, Gittenberger-de Groot, Adriana C, Feng, Qingping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942143/
https://www.ncbi.nlm.nih.gov/pubmed/24533448
http://dx.doi.org/10.1186/1475-2840-13-46

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942143/
https://www.ncbi.nlm.nih.gov/pubmed/24533448
http://dx.doi.org/10.1186/1475-2840-13-46

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