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Transcriptional and functional profiling of human intestinal dendritic cells reveals conserved specialization and a role for Bcl-6 and Blimp-1 in terminal subset differentiation
Dendritic cells (DCs) that orchestrate mucosal immunity have been studied in mice. Here we characterize human gut DC populations, and define their relationship to previously studied human and mouse DCs. CD103(+)Sirpα(−) DCs were related to human blood CD141(+) and to mouse intestinal CD103(+)CD11b(−...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942165/ https://www.ncbi.nlm.nih.gov/pubmed/24292363 http://dx.doi.org/10.1038/ni.2768 |