Transcriptional and functional profiling of human intestinal dendritic cells reveals conserved specialization and a role for Bcl-6 and Blimp-1 in terminal subset differentiation

Dendritic cells (DCs) that orchestrate mucosal immunity have been studied in mice. Here we characterize human gut DC populations, and define their relationship to previously studied human and mouse DCs. CD103(+)Sirpα(−) DCs were related to human blood CD141(+) and to mouse intestinal CD103(+)CD11b(−...

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Detalles Bibliográficos
Autores principales: Watchmaker, Payal B., Lahl, Katharina, Lee, Mike, Baumjohann, Dirk, Morton, John, Kim, Sun Jung, Zeng, Ruizhu, Dent, Alexander, Ansel, K. Mark, Diamond, Betty, Hadeiba, Husein, Butcher, Eugene C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942165/
https://www.ncbi.nlm.nih.gov/pubmed/24292363
http://dx.doi.org/10.1038/ni.2768

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