Antiaging Properties of a Grape-Derived Antioxidant Are Regulated by Mitochondrial Balance of Fusion and Fission Leading to Mitophagy Triggered by a Signaling Network of Sirt1-Sirt3-Foxo3-PINK1-PARKIN

It was proposed that resveratrol, a polyphenolic antioxidant and a calorie restriction mimetic could promote longevity but subsequent studies could not prove this. The original proposal was based on the fact that a grape-derived antioxidant could activate the antiaging gene Sirt1. Most studies agree...

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Detalles Bibliográficos
Autores principales: Das, Somak, Mitrovsky, Goran, Vasanthi, Hannah R., Das, Dipak K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942197/
https://www.ncbi.nlm.nih.gov/pubmed/24669285
http://dx.doi.org/10.1155/2014/345105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942197/
https://www.ncbi.nlm.nih.gov/pubmed/24669285
http://dx.doi.org/10.1155/2014/345105

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