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Structural Insights Into DNA Repair by RNase T—An Exonuclease Processing 3′ End of Structured DNA in Repair Pathways

DNA repair mechanisms are essential for preservation of genome integrity. However, it is not clear how DNA are selected and processed at broken ends by exonucleases during repair pathways. Here we show that the DnaQ-like exonuclease RNase T is critical for Escherichia coli resistance to various DNA-...

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Detalles Bibliográficos
Autores principales: Hsiao, Yu-Yuan, Fang, Woei-Horng, Lee, Chia-Chia, Chen, Yi-Ping, Yuan, Hanna S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942315/
https://www.ncbi.nlm.nih.gov/pubmed/24594808
http://dx.doi.org/10.1371/journal.pbio.1001803