Cargando…
Structural Insights Into DNA Repair by RNase T—An Exonuclease Processing 3′ End of Structured DNA in Repair Pathways
DNA repair mechanisms are essential for preservation of genome integrity. However, it is not clear how DNA are selected and processed at broken ends by exonucleases during repair pathways. Here we show that the DnaQ-like exonuclease RNase T is critical for Escherichia coli resistance to various DNA-...
Autores principales: | Hsiao, Yu-Yuan, Fang, Woei-Horng, Lee, Chia-Chia, Chen, Yi-Ping, Yuan, Hanna S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942315/ https://www.ncbi.nlm.nih.gov/pubmed/24594808 http://dx.doi.org/10.1371/journal.pbio.1001803 |
Ejemplares similares
-
Structure and function of TatD exonuclease in DNA repair
por: Chen, Yi-Chen, et al.
Publicado: (2014) -
How an exonuclease decides where to stop in trimming of nucleic acids: crystal structures of RNase T–product complexes
por: Hsiao, Yu-Yuan, et al.
Publicado: (2012) -
Structural insights into catalysis and dimerization enhanced exonuclease activity of RNase J
por: Zhao, Ye, et al.
Publicado: (2015) -
Architecture of the Pol III–clamp–exonuclease complex reveals key roles of the exonuclease subunit in processive DNA synthesis and repair
por: Toste Rêgo, Ana, et al.
Publicado: (2013) -
Delineation of structural domains and identification of functionally important residues in DNA repair enzyme exonuclease VII
por: Poleszak, Katarzyna, et al.
Publicado: (2012)