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Th1 Response and Systemic Treg Deficiency in Inclusion Body Myositis

OBJECTIVE: Sporadic inclusion body myositis (sIBM), the most frequent myositis in elderly patients, is characterized by the presence muscle inflammation and degeneration. We aimed at characterizing immune responses and regulatory T cells, considered key players in the maintenance of peripheral immun...

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Detalles Bibliográficos
Autores principales: Allenbach, Yves, Chaara, Wahiba, Rosenzwajg, Michelle, Six, Adrien, Prevel, Nicolas, Mingozzi, Federico, Wanschitz, Julia, Musset, Lucile, Charuel, Jean-Luc, Eymard, Bruno, Salomon, Benoit, Duyckaerts, Charles, Maisonobe, Thierry, Dubourg, Odile, Herson, Serge, Klatzmann, David, Benveniste, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942319/
https://www.ncbi.nlm.nih.gov/pubmed/24594700
http://dx.doi.org/10.1371/journal.pone.0088788