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Phosphoinositide Metabolism Links cGMP-Dependent Protein Kinase G to Essential Ca(2+) Signals at Key Decision Points in the Life Cycle of Malaria Parasites
Many critical events in the Plasmodium life cycle rely on the controlled release of Ca(2+) from intracellular stores to activate stage-specific Ca(2+)-dependent protein kinases. Using the motility of Plasmodium berghei ookinetes as a signalling paradigm, we show that the cyclic guanosine monophospha...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942320/ https://www.ncbi.nlm.nih.gov/pubmed/24594931 http://dx.doi.org/10.1371/journal.pbio.1001806 |