Phosphoinositide Metabolism Links cGMP-Dependent Protein Kinase G to Essential Ca(2+) Signals at Key Decision Points in the Life Cycle of Malaria Parasites

Many critical events in the Plasmodium life cycle rely on the controlled release of Ca(2+) from intracellular stores to activate stage-specific Ca(2+)-dependent protein kinases. Using the motility of Plasmodium berghei ookinetes as a signalling paradigm, we show that the cyclic guanosine monophospha...

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Detalles Bibliográficos
Autores principales: Brochet, Mathieu, Collins, Mark O., Smith, Terry K., Thompson, Eloise, Sebastian, Sarah, Volkmann, Katrin, Schwach, Frank, Chappell, Lia, Gomes, Ana Rita, Berriman, Matthew, Rayner, Julian C., Baker, David A., Choudhary, Jyoti, Billker, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942320/
https://www.ncbi.nlm.nih.gov/pubmed/24594931
http://dx.doi.org/10.1371/journal.pbio.1001806

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