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Activating the Expression of Human K-ras(G12D) Stimulates Oncogenic Transformation in Transgenic Goat Fetal Fibroblast Cells

Humane use of preclinical large animal cancer models plays a critical role in understanding cancer biology and developing therapeutic treatments. Among the large animal candidates, goats have great potentials as sustainable sources for large animal cancer model development. Goats are easier to handl...

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Detalles Bibliográficos
Autores principales: Gong, Jianhua, Wang, Zhongde, Polejaeva, Irina, Salgia, Ravi, Kao, Chien-Min, Chen, Chin-Tu, Chen, Guangchun, Chen, Liaohai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942380/
https://www.ncbi.nlm.nih.gov/pubmed/24594684
http://dx.doi.org/10.1371/journal.pone.0090059