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Activating the Expression of Human K-ras(G12D) Stimulates Oncogenic Transformation in Transgenic Goat Fetal Fibroblast Cells
Humane use of preclinical large animal cancer models plays a critical role in understanding cancer biology and developing therapeutic treatments. Among the large animal candidates, goats have great potentials as sustainable sources for large animal cancer model development. Goats are easier to handl...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942380/ https://www.ncbi.nlm.nih.gov/pubmed/24594684 http://dx.doi.org/10.1371/journal.pone.0090059 |