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First In-Mouse Development and Application of a Surgically Relevant Xenograft Model of Ovarian Carcinoma

PURPOSE: Preclinical models of epithelial ovarian cancer have not been exploited to evaluate the clinical standard combination therapy of surgical debulking with follow-up chemotherapy. As surgery is critical to patient survival, here we establish a combined surgical/chemotherapy xenograft model of...

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Detalles Bibliográficos
Autores principales: Helland, Øystein, Popa, Mihaela, Vintermyr, Olav K., Molven, Anders, Gjertsen, Bjørn Tore, Bjørge, Line, McCormack, Emmet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942384/
https://www.ncbi.nlm.nih.gov/pubmed/24594904
http://dx.doi.org/10.1371/journal.pone.0089527