Effects of Downregulation of MicroRNA-181a on H(2)O(2)-Induced H9c2 Cell Apoptosis via the Mitochondrial Apoptotic Pathway

Glutathione peroxidase-1 (GPx1) is a pivotal intracellular antioxidant enzyme that enzymatically reduces hydrogen peroxide to water to limit its harmful effects. This study aims to identify a microRNA (miRNA) that targets GPx1 to maintain redox homeostasis. Dual luciferase assays combined with mutat...

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Detalles Bibliográficos
Autores principales: Wang, Lei, Huang, He, Fan, Yang, Kong, Bin, Hu, He, Hu, Ke, Guo, Jun, Mei, Yang, Liu, Wan-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942394/
https://www.ncbi.nlm.nih.gov/pubmed/24683439
http://dx.doi.org/10.1155/2014/960362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942394/
https://www.ncbi.nlm.nih.gov/pubmed/24683439
http://dx.doi.org/10.1155/2014/960362

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