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βig-h3 Promotes Human Osteosarcoma Cells Metastasis by Interacting with Integrin α2β1 and Activating PI3K Signaling Pathway

Osteosarcoma, the most common primary bone tumor in children and young adolescents, is characterized by local invasion and distant metastasis. But the detailed mechanisms of osteosarcoma metastasis are not well known. In the present study, we found that βig-h3 promotes metastatic potential of human...

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Detalles Bibliográficos
Autores principales: Guo, Yun-Shan, Zhao, Rui, Ma, Jie, Cui, Wei, Sun, Zhen, Gao, Bo, He, Shu, Han, Yue-Hu, Fan, Jing, Yang, Liu, Tang, Juan, Luo, Zhuo-Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942417/
https://www.ncbi.nlm.nih.gov/pubmed/24595049
http://dx.doi.org/10.1371/journal.pone.0090220